From Reuters:

WASHINGTON (Reuters) - President George W. Bush suffered a major defeat on his plan to overhaul immigration laws on Thursday when the Senate refused to close debate and advance the legislation.

The bill that would have given a path to U.S. citizenship for millions of illegal immigrants fell 14 votes short of the 60 needed in the 100-member Senate to advance toward a final vote.

Bush has sought an overhaul of U.S. immigration laws for years and this bill may have been his last chance for a significant domestic legislative victory before leaving office when his second term ends in a year and a half.